A mysterious illness, referred to as “disease X” by the Africa Centers for Disease Control and Prevention, has claimed the lives of at least 31 people in the remote Panzi region of the Democratic Republic of Congo (DRC). The World Health Organization (WHO) reports that the majority of the victims are children, with more than half of the deaths occurring in children under five years old, many of whom were severely malnourished. The illness has affected the Kwango Province, located 435 miles southeast of the capital, Kinshasa, with 406 reported cases so far.
The exact death toll remains unclear, with some reports suggesting that up to 143 people may have died from the disease. A WHO team has been deployed to the region to investigate the outbreak, which is believed to have begun circulating in October. The DRC’s Ministry of Public Health alerted the WHO about the increase in deaths on October 29, and by December 5, they confirmed a mortality rate of about 8%, with several deaths occurring outside of health facilities. The community deaths have raised significant concern among local health officials.
The symptoms of the mysterious illness are similar to those of a respiratory infection, including fever, headaches, coughing, body aches, and runny noses. The WHO’s response teams are actively working on identifying the cause of the disease. They are collecting samples for laboratory testing, gathering detailed clinical data, and investigating transmission patterns. The WHO has considered several potential causes for the outbreak, including acute pneumonia, influenza, COVID-19, measles, malaria, and the possibility that malnutrition is exacerbating the situation.
The outbreak is occurring in a remote and difficult-to-access area, about two days’ travel by road from Kinshasa. The region is currently in the rainy season, which increases the prevalence of malaria, further complicating efforts to address the situation. Additionally, the area lacks a functional laboratory, and communication infrastructure is limited. The presence of armed groups in the region also poses a significant threat to the safety and effectiveness of the response efforts.
Although the WHO has stated that the global risk remains low, concerns about the spread of the disease persist due to its proximity to the border with Angola. Experts have not ruled out the possibility that the disease may be airborne, raising fears of cross-border transmission. The WHO is closely monitoring the situation, deploying resources to better understand and contain the outbreak, and ensuring that the response is coordinated effectively despite the many challenges posed by the remote location and ongoing security issues.