Pharmaceutical and biotechnological industries work to formulate various drugs in different dosage forms. However, every industry has a specific unit separate for each dosage form.
AVKARE is an American Industry that formulates pharmaceuticals and infection control products. The firm manufactures medicines for erectile dysfunction and depression as well. Furthermore, the company produces various medicines, including drugs for cardiovascular disease treatment, antibiotics, vitamins, and mineral supplements. Recently, the pharmaceutical industry has called two of its medications voluntary. Because by mistake, these medications got packaged together at a third-party facility.
AVKARE Sildenafil – A Drug For Erectile Dysfunction
The company produces multiple drugs, but recently one of its medications for erectile dysfunction got accidentally mixed with its anti-depressive medication. Sildenafil is a drug that doctors prescribe for the treatment of erectile dysfunction. It is available in three doses of 25mg, 50mg, and 100mg.
Sildenafil is a film-coated tablet, and the active ingredient in it is Viagra, which is a PDE-5 inhibitor. The tablets may interact with nitrates. Due to these interactions, the dose and timing of administration need modification if the person takes other medicines as well.
Sildenafil is a prescription-only drug that is for dispensing it to the purchaser, an official prescription from the physician is essential. Taking sildenafil unintentionally can be a problem for individuals, particularly those who have an underlying disease condition.
Cardiac patients take drugs that contain nitrates, to which Sildenafil interacts and cause lowering of blood pressure to dangerous levels. Similarly, other medications like medicines for diabetes, hypertension, or cardiovascular diseases also have nitrates in them. This combination of nitrates and Sildenafil can be lethal especially if the doses are high.
Trazodone Hydrochloride AVKARE Antidepressant
Sildenafil 100mg Tablet with lot number 36884 and expiration date of 03/2022, is accidentally mixed with Trazodone Hydrochloride 100mg Tablet – lot number 36783 and expiration date 06/2022. Due to the inadvertent mix-up of drugs, the manufacturing company recalls the medications of these lots.
Trazodone Hydrochloride is a major-drug for depressive disorder. To pack these tablets, 1000 count bottles are available. Moreover, trazodone Hydrochloride treats depressive conditions, anxiety, and stress.
However, people who have a sensitivity to the active substance or any excipient in the pharmaceutical formulation may show hypersensitivity. In addition, trazodone hydrochloride interacts with people with underlying disease conditions or are patients with acute myocardial infarction. Trazadone Hydrochloride can cause toxicity if taken with alcohol or other hypnotics.
If someone accidentally takes the drug, it can cause adverse effects such as sedation, dizziness, constipation, and blurred vision. Trazadone Hydrochloride may also increase the risk of falling in elderly patients and may lead to serious-fractures.
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Impact of Such Events
There are chances of the occurrence of errors in any place or profession, but these mistakes can result in lethal outcomes. Any wrong step in the pharmaceutical industry can cause many people to lose their lives. Also, the company suffers a lot as their repute and name gets negative publicity. As well as, the company suffers economic losses, but the loss of cash is negligible in comparison with the loss of lives.
Thus, the workers of any field, particularly workers of the professional-fields that provide healthcare facilities, need to be extra cautious about their actions. Fortunately, the mix-up of Sildenafil and Trazodone does not cause any severe lethal outcomes.
The company, as soon as it came to know of the situation, voluntarily called off the sale of these medications. Moreover, AvKARE has asked the distributors to return the mix-up-lots of Sildenafil and Trazodone Hydrochloride.